UN/NA Number Reference
DOT Class 6.1 Toxic Substance placard

UN 2290: Isophorone diisocyanate

49 CFR 172.101 Hazardous Materials Table·ERG 2024

DOT Classification and Shipping

UN 2290 is assigned the proper shipping name Isophorone diisocyanate in the U.S. DOT Hazardous Materials Table (49 CFR 172.101). It is classified as a Class 6.1 Toxic Substance material, Packing Group III. Required label(s): 6.1.

Packing group indicates the degree of danger within a hazard class: PG I is high danger, PG II medium, PG III low. The proper shipping name, hazard class, UN number, and packing group together form the basic shipping description that must appear on shipping papers and, where required, on the package and placard.

Emergency Response (ERG Guide 156)

Hazards: TOXIC or CORROSIVE. FLAMMABLE. Vapors may travel to ignition source.

Fire: Alcohol-resistant foam, dry chemical, CO2. Water spray for cooling only.

Spill: Eliminate ignition sources. Do not touch. Ventilate area.

Chemical and Physical Properties

Isophorone diisocyanate appears as a clear to light-yellow liquid. Slightly denser than water and insoluble in water. Toxic by inhalation and skin absorption. Very irritating to skin. Used to make polyurethane coatings.

CAS Number: 4098-71-9
Molecular Formula: C12H18N2O2
Molecular Weight: 222.28 g/mol
Color / Form: Colorless to slightly yellow liquid
Odor: Pungent
Boiling Point: 316 F
Melting Point: -76 °F (NTP, 1992)
Flash Point: greater than 200 F
Autoignition: 430 °C
Specific Gravity: 1.056 to 1.062
Vapor Pressure: 0.0003 mmHg at 68 F
Water Solubility: less than 1 mg/mL at 77 F
Log P: 4.75 (calculated)

Regulatory Data

CERCLA RQ (40 CFR 302.4)
1 lb
EPCRA TPQ (40 CFR 355)
500 lb
OSHA PEL
none
NIOSH REL
TWA 0.005 ppm (0.045 mg/m 3 ) ST 0.02 ppm (0.180 mg/m 3 ) [skin]
IDLH
N

A release of this material at or above its CERCLA reportable quantity (1 lb) requires immediate notification to the National Response Center at 800-424-8802.

Special Provisions

49 CFR 172.102 special provision codes for this entry: IB3, T4, TP2. These codes modify the general requirements (packaging, quantity limits, exceptions) for this specific material. Look up each code in 49 CFR 172.102 for the full text.

Need the full interactive record? Open UN 2290 in the SpillNerd lookup tool for the live database entry with placard graphics, GHS pictograms, full segregation tables, and synonym search. For another material, use the UN number and chemical lookup.

Reference data compiled from the DOT Hazardous Materials Table (49 CFR 172.101), the 2024 Emergency Response Guidebook, and public chemical databases (PubChem, NIOSH, EPA). Always verify the correct shipping description against the current regulation and the manufacturer's SDS Section 14 before shipping.